4OKP
Crystal structure of AmpC beta-lactamase in complex with the product form of 7-amino-desacetoxycephalosporanic acid
Summary for 4OKP
Entry DOI | 10.2210/pdb4okp/pdb |
Related | 1kvl 1kvm 4OLD |
Descriptor | Beta-lactamase, PHOSPHATE ION, (2R)-2-[(R)-amino(carboxy)methyl]-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, ... (4 entities in total) |
Functional Keywords | ampc beta-lactamase, class c, hydrolase, cephalosporinase |
Biological source | Escherichia coli |
Cellular location | Periplasm: P00811 |
Total number of polymer chains | 2 |
Total formula weight | 79598.04 |
Authors | Barelier, S.B.,Shoichet, B.K. (deposition date: 2014-01-22, release date: 2014-05-28, Last modification date: 2024-02-28) |
Primary citation | Barelier, S.,Cummings, J.A.,Rauwerdink, A.M.,Hitchcock, D.S.,Farelli, J.D.,Almo, S.C.,Raushel, F.M.,Allen, K.N.,Shoichet, B.K. Substrate deconstruction and the nonadditivity of enzyme recognition. J.Am.Chem.Soc., 136:7374-7382, 2014 Cited by PubMed: 24791931DOI: 10.1021/ja501354q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.37 Å) |
Structure validation
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