4OII

West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab

4OII の概要

• エントリーDOI: 10.2210/pdb4oii/pdb
• 関連するPDBエントリー: 4OIE 4OIG
• 分子名称: NON-STRUCTURAL PROTEIN NS1, Light Chain of Fab fragment of 22NS1 Antibody, Heavy Chain of Fab fragment of 22NS1 Antibody, ... (4 entities in total)
• 機能のキーワード: west nile virus, antibody, fab, neutralizing, flavivirus, non-structural protein, ns1, viral protein-immune system complex, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein/immune system
• 由来する生物種: West Nile virus (WNV); 詳細
• 細胞内の位置: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Lumenal side . Host nucleus . Secreted . Virion membrane ; Multi-pass membrane protein : U3N977
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 135472.64

構造登録者

Edeling, M.A.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2014-01-19, 公開日: 2014-03-05, 最終更新日: 2017-11-22)

• 主引用文献: Edeling, M.A.,Diamond, M.S.,Fremont, D.H.; Structural basis of Flavivirus NS1 assembly and antibody recognition.; Proc.Natl.Acad.Sci.USA, 111:4285-4290, 2014; PubMed: 24594604; DOI: 10.1073/pnas.1322036111

実験手法

X-RAY DIFFRACTION (3 Å)