4OHF

Crystal structure of cytosolic nucleotidase II (LPG0095) in complex with GMP from Legionella pneumophila, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET LGR1

4OHF の概要

• エントリーDOI: 10.2210/pdb4ohf/pdb
• 関連するPDBエントリー: 4G63
• 分子名称: Cytosolic IMP-GMP specific 5'-nucleotidase, GUANOSINE-5'-MONOPHOSPHATE, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: structural genomics, psi-biology, northeast structural genomics consortium, nesg, 3-domained structure that resembles had, nucleotidase. it catalyzes the breakdown of selected nucleoside monophosphates, cytosol, hydrolase
• 由来する生物種: Legionella pneumophila subsp. pneumophila
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 220505.06

構造登録者

Srinivisan, B.,Forouhar, F.,Shukla, A.,Sampangi, C.,Kulkarni, S.,Abashidze, M.,Seetharaman, J.,Lew, S.,Mao, L.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.M.,Tong, L.,Balaram, H.,Northeast Structural Genomics Consortium (NESG) (登録日: 2014-01-17, 公開日: 2014-02-26, 最終更新日: 2023-09-20)

• 主引用文献: Srinivasan, B.,Forouhar, F.,Shukla, A.,Sampangi, C.,Kulkarni, S.,Abashidze, M.,Seetharaman, J.,Lew, S.,Mao, L.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Tong, L.,Balaram, H.; Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila.; Febs J., 281:1613-1628, 2014; PubMed: 24456211; DOI: 10.1111/febs.12727

実験手法

X-RAY DIFFRACTION (2.53 Å)