4OFZ
Structure of unliganded trehalose-6-phosphate phosphatase from Brugia malayi
Summary for 4OFZ
Entry DOI | 10.2210/pdb4ofz/pdb |
Descriptor | Trehalose-phosphatase, MAGNESIUM ION (3 entities in total) |
Functional Keywords | had superfamily/rossmann fold, trehalose-6-phosphate phosphohydrolase, hydrolase |
Biological source | Brugia malayi (agent of lymphatic filariasis) |
Total number of polymer chains | 1 |
Total formula weight | 57681.60 |
Authors | Farelli, J.D.,Allen, K.N.,Carlow, C.K.S.,Dunaway-Mariano, D. (deposition date: 2014-01-15, release date: 2014-07-16, Last modification date: 2018-01-24) |
Primary citation | Farelli, J.D.,Galvin, B.D.,Li, Z.,Liu, C.,Aono, M.,Garland, M.,Hallett, O.E.,Causey, T.B.,Ali-Reynolds, A.,Saltzberg, D.J.,Carlow, C.K.,Dunaway-Mariano, D.,Allen, K.N. Structure of the Trehalose-6-phosphate Phosphatase from Brugia malayi Reveals Key Design Principles for Anthelmintic Drugs. Plos Pathog., 10:e1004245-e1004245, 2014 Cited by PubMed: 24992307DOI: 10.1371/journal.ppat.1004245 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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