4OFZ

Structure of unliganded trehalose-6-phosphate phosphatase from Brugia malayi

4OFZ の概要

• エントリーDOI: 10.2210/pdb4ofz/pdb
• 分子名称: Trehalose-phosphatase, MAGNESIUM ION (3 entities in total)
• 機能のキーワード: had superfamily/rossmann fold, trehalose-6-phosphate phosphohydrolase, hydrolase
• 由来する生物種: Brugia malayi (agent of lymphatic filariasis)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 57681.60

構造登録者

Farelli, J.D.,Allen, K.N.,Carlow, C.K.S.,Dunaway-Mariano, D. (登録日: 2014-01-15, 公開日: 2014-07-16, 最終更新日: 2018-01-24)

• 主引用文献: Farelli, J.D.,Galvin, B.D.,Li, Z.,Liu, C.,Aono, M.,Garland, M.,Hallett, O.E.,Causey, T.B.,Ali-Reynolds, A.,Saltzberg, D.J.,Carlow, C.K.,Dunaway-Mariano, D.,Allen, K.N.; Structure of the Trehalose-6-phosphate Phosphatase from Brugia malayi Reveals Key Design Principles for Anthelmintic Drugs.; Plos Pathog., 10:e1004245-e1004245, 2014; PubMed: 24992307; DOI: 10.1371/journal.ppat.1004245

実験手法

X-RAY DIFFRACTION (3 Å)