4OCD

In and Out the minor groove: Interaction of an AT rich-DNA with the CD27 drug

4OCD の概要

• エントリーDOI: 10.2210/pdb4ocd/pdb
• 分子名称: d(AAAATTTT), N1-(4,5-dihydro-1H-imidazol-2-yl)-N4-(4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)benzene-1,4-diamine (3 entities in total)
• 機能のキーワード: dna minor groove binding drugs, all-at dna, dicationic drug, imidazoline drug, dna
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 8280.14

構造登録者

Acosta-Reyes, F.J.,Dardonville, C.,de Koning, H.P.,Natto, M.,Subirana, J.A.,Campos, J.L. (登録日: 2014-01-08, 公開日: 2014-06-11, 最終更新日: 2024-02-28)

• 主引用文献: Acosta-Reyes, F.J.,Dardonville, C.,de Koning, H.P.,Natto, M.,Subirana, J.A.,Campos, J.L.; In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27; Acta Crystallogr.,Sect.D, D70:1614-1621, 2014; PubMed: 24914972; DOI: 10.1107/S139900471400697X

実験手法

X-RAY DIFFRACTION (2.1 Å)