4OCA

Cryatal structure of ArnB K188A complexted with PLP and UDP-Ara4N

4OCA の概要

• エントリーDOI: 10.2210/pdb4oca/pdb
• 分子名称: UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, (2R,3R,4S,5S)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]tetrahydro-2H-pyr an-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (3 entities in total)
• 機能のキーワード: aminotransferase, transferase
• 由来する生物種: Salmonella enterica subsp. enterica serovar Typhimurium
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42567.12

構造登録者

Sousa, M.C.,Lee, M. (登録日: 2014-01-08, 公開日: 2014-03-12, 最終更新日: 2024-02-28)

• 主引用文献: Lee, M.,Sousa, M.C.; Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria.; Biochemistry, 53:796-805, 2014; PubMed: 24460375; DOI: 10.1021/bi4015677

実験手法

X-RAY DIFFRACTION (2.3 Å)