4O9T

Mechanism of transhydrogenase coupling proton translocation and hydride transfer

Summary for 4O9T

Entry DOI	10.2210/pdb4o9t/pdb
Descriptor	NAD(P) transhydrogenase subunit alpha 2, NAD(P) transhydrogenase subunit beta (2 entities in total)
Functional Keywords	nicotinamide nucleotide transhydrogenase couples the proton motive force to nadph formation, integral membrane component of thermus thermophilus transhydrogenase, respiratory enzyme, protons and nad(h), nadp(h), proton translocation and hydride transfer, periplasmic membrane and cytosol, membrane protein
Biological source	Thermus thermophilus More
Total number of polymer chains	8
Total formula weight	160618.81
Authors	Leung, J.H.,Yamaguchi, M.,Moeller, A.,Schurig-Briccio, L.A.,Gennis, R.B.,Potter, C.S.,Carragher, B.,Stout, C.D. (deposition date: 2014-01-02, release date: 2014-06-11, Last modification date: 2024-02-28)
Primary citation	Leung, J.H.,Schurig-Briccio, L.A.,Yamaguchi, M.,Moeller, A.,Speir, J.A.,Gennis, R.B.,Stout, C.D. Structural biology. Division of labor in transhydrogenase by alternating proton translocation and hydride transfer. Science, 347:178-181, 2015 Cited by PubMed: 25574024 DOI: 10.1126/science.1260451 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.079 Å)

Structure validation