4O5C
Structure of human DNA polymerase complexed with N7-MG as the template base in a 1-nucleotide gapped DNA
Summary for 4O5C
Entry DOI | 10.2210/pdb4o5c/pdb |
Related | 1BPX 3ISB 4O5E 4O5K |
Descriptor | DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... (6 entities in total) |
Functional Keywords | dna binding, polymerase fold, nucleotidyl transfer, dna, nucleus, transferase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P06746 |
Total number of polymer chains | 4 |
Total formula weight | 47080.98 |
Authors | Koag, M.C.,Lee, S. (deposition date: 2013-12-19, release date: 2014-07-02, Last modification date: 2024-02-28) |
Primary citation | Koag, M.C.,Kou, Y.,Ouzon-Shubeita, H.,Lee, S. Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine. Nucleic Acids Res., 42:8755-8766, 2014 Cited by PubMed: 24966350DOI: 10.1093/nar/gku554 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.363 Å) |
Structure validation
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