4O4Z

MURINE NEUROGLOBIN UNDER 30 BAR PRESSURE NITROUS Oxide

4O4Z の概要

• エントリーDOI: 10.2210/pdb4o4z/pdb
• 関連するPDBエントリー: 4NWE 4NWH 4NXA 4NXC 4O4T
• 分子名称: Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: globin, oxygen storage-transport protein complex, oxygen storage/transport protein
• 由来する生物種: Mus musculus (mouse)
• 細胞内の位置: Perikaryon : Q9ER97
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18239.19

構造登録者

Colloc'h, N.,Prange, T.,Vallone, B. (登録日: 2013-12-19, 公開日: 2014-09-24, 最終更新日: 2023-11-08)

主引用文献

Abraini, J.H.,Marassio, G.,David, H.N.,Vallone, B.,Prange, T.,Colloc'h, N.
Crystallographic Studies with Xenon and Nitrous Oxide Provide Evidence for Protein-dependent Processes in the Mechanisms of General Anesthesia
Anesthesiology, 121:1018-1027, 2014

PubMed Abstract: The mechanisms by which general anesthetics, including xenon and nitrous oxide, act are only beginning to be discovered. However, structural approaches revealed weak but specific protein-gas interactions.

PubMed: 25211169
DOI: 10.1097/ALN.0000000000000435

実験手法

X-RAY DIFFRACTION (1.7 Å)