4O4T

MURINE NEUROGLOBIN UNDER XENON PRESSURE 30 bar

Summary for 4O4T

• Entry DOI: 10.2210/pdb4o4t/pdb
• Related: 4NWE 4NWH 4NXA 4NXC 4O4Z
• Descriptor: Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... (5 entities in total)
• Functional Keywords: globin, oxygen storage-transport protein complex, oxygen storage/transport protein
• Biological source: Mus musculus (mouse)
• Cellular location: Perikaryon : Q9ER97
• Total number of polymer chains: 1
• Total formula weight: 18938.17

Authors

Colloc'h, N.,Prange, T.,Vallone, B. (deposition date: 2013-12-19, release date: 2014-09-24, Last modification date: 2023-11-08)

Primary citation

Abraini, J.H.,Marassio, G.,David, H.N.,Vallone, B.,Prange, T.,Colloc'h, N.
Crystallographic Studies with Xenon and Nitrous Oxide Provide Evidence for Protein-dependent Processes in the Mechanisms of General Anesthesia
Anesthesiology, 121:1018-1027, 2014

PubMed Abstract: The mechanisms by which general anesthetics, including xenon and nitrous oxide, act are only beginning to be discovered. However, structural approaches revealed weak but specific protein-gas interactions.

PubMed: 25211169
DOI: 10.1097/ALN.0000000000000435

Experimental method

X-RAY DIFFRACTION (1.9 Å)