4O1G
MTB adenosine kinase in complex with gamma-Thio-ATP
Summary for 4O1G
Entry DOI | 10.2210/pdb4o1g/pdb |
Descriptor | Adenosine kinase, SODIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... (4 entities in total) |
Functional Keywords | adenosine kinase, transferase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 35050.19 |
Authors | Dostal, J.,Brynda, J.,Hocek, M.,Pichova, I. (deposition date: 2013-12-15, release date: 2014-11-26, Last modification date: 2024-03-20) |
Primary citation | Snasel, J.,Naus, P.,Dostal, J.,Hnizda, A.,Fanfrlik, J.,Brynda, J.,Bourderioux, A.,Dusek, M.,Dvorakova, H.,Stolarikova, J.,Zabranska, H.,Pohl, R.,Konecny, P.,Dzubak, P.,Votruba, I.,Hajduch, M.,Rezacova, P.,Veverka, V.,Hocek, M.,Pichova, I. Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides J.Med.Chem., 57:8268-8279, 2014 Cited by PubMed: 25259627DOI: 10.1021/jm500497v PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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