4NZQ

Crystal structure of Ca2+-free prothrombin deletion mutant residues 146-167

Summary for 4NZQ

• Entry DOI: 10.2210/pdb4nzq/pdb
• Related: 2PF1 3NXP 4O03
• Descriptor: Prothrombin, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: prothrombin, kringle, serine protease, coagulation, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 64221.29

Authors

Pozzi, N.,Chen, Z.,Shropshire, D.B.,Pelc, L.A.,Di Cera, E. (deposition date: 2013-12-12, release date: 2014-05-21, Last modification date: 2023-12-06)

• Primary citation: Pozzi, N.,Chen, Z.,Pelc, L.A.,Shropshire, D.B.,Di Cera, E.; The linker connecting the two kringles plays a key role in prothrombin activation.; Proc.Natl.Acad.Sci.USA, 111:7630-7635, 2014; PubMed: 24821807; DOI: 10.1073/pnas.1403779111

Experimental method

X-RAY DIFFRACTION (2.807 Å)