4NZL

Extracellular proteins of Staphylococcus aureus inhibit the neutrophil serine proteases

4NZL の概要

• エントリーDOI: 10.2210/pdb4nzl/pdb
• 分子名称: Neutrophil elastase, Uncharacterized protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: primarily beta, serine protease, protease inhibitor, innate immunity, azurophilic granules, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Staphylococcus aureus subsp. aureus; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 37506.63

構造登録者

Stapels, D.A.C.,von Koeckritz-Blickwede, M.,Ramyar, K.X.,Bischoff, M.,Milder, F.,Ruyken, M.,Scheepmaker, L.,McWhorter, W.J.,Herrmann, M.,van Kessel, K.P.M.,Geisbrecht, B.V.,Rooijakkers, S.H.M. (登録日: 2013-12-12, 公開日: 2014-08-20, 最終更新日: 2023-09-20)

• 主引用文献: Stapels, D.A.,Ramyar, K.X.,Bischoff, M.,von Kockritz-Blickwede, M.,Milder, F.J.,Ruyken, M.,Eisenbeis, J.,McWhorter, W.J.,Herrmann, M.,van Kessel, K.P.,Geisbrecht, B.V.,Rooijakkers, S.H.; Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors.; Proc.Natl.Acad.Sci.USA, 111:13187-13192, 2014; PubMed: 25161283; DOI: 10.1073/pnas.1407616111

実験手法

X-RAY DIFFRACTION (1.85 Å)