4NZG

Crystal Structure of the N-terminal domain of Moloney murine leukemia virus integrase, Northeast Structural Genomics Consortium Target OR3

Summary for 4NZG

• Entry DOI: 10.2210/pdb4nzg/pdb
• Related: 3NNQ
• Descriptor: Integrase p46, ZINC ION, ACETATE ION, ... (5 entities in total)
• Functional Keywords: structural genomics, psi-biology, protein structure initiative, northeast structural genomics consortium, nesg, retroviral integrase, zn finger, viral protein
• Biological source: Moloney murine leukemia virus (MoMLV)
• Cellular location: Gag-Pol polyprotein: Host cell membrane ; Lipid-anchor . Matrix protein p15: Virion . Capsid protein p30: Virion . Nucleocapsid protein p10: Virion : P03355
• Total number of polymer chains: 4
• Total formula weight: 48832.96

Authors

Guan, R.,Jiang, M.,Janjua, H.,Maglaqui, M.,Zhao, L.,Xiao, R.,Acton, T.B.,Everett, J.K.,Roth, M.,Montelione, G.T.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2013-12-12, release date: 2014-02-05, Last modification date: 2023-09-20)

• Primary citation: Guan, R.,Aiyer, S.,Cote, M.L.,Xiao, R.,Jiang, M.,Acton, T.B.,Roth, M.J.,Montelione, G.T.; X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition.; Proteins, 85:647-656, 2017; PubMed: 28066922; DOI: 10.1002/prot.25245

Experimental method

X-RAY DIFFRACTION (2.152 Å)