4NYZ
The EMCV 3Dpol structure with altered motif A conformation at 2.15A resolution
Summary for 4NYZ
Entry DOI | 10.2210/pdb4nyz/pdb |
Related | 1U09 4nz0 |
Descriptor | Genome polyprotein, GLUTAMINE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | encephalomyocarditis virus, close right hand, rna dependent rna polymerase, transferase |
Biological source | Mengo virus |
Cellular location | Protein 2A: Host nucleus . Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3B: Virion . Protease 3C: Host cytoplasm . RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P12296 |
Total number of polymer chains | 1 |
Total formula weight | 52474.98 |
Authors | Vives-adrian, L.,Lujan, C.,Ferrer-orta, C.,Verdaguer, N. (deposition date: 2013-12-11, release date: 2014-03-19, Last modification date: 2023-11-08) |
Primary citation | Vives-Adrian, L.,Lujan, C.,Oliva, B.,van der Linden, L.,Selisko, B.,Coutard, B.,Canard, B.,van Kuppeveld, F.J.,Ferrer-Orta, C.,Verdaguer, N. The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site J.Virol., 88:5595-5607, 2014 Cited by PubMed: 24600002DOI: 10.1128/JVI.03502-13 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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