4NXI

Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis

Summary for 4NXI

• Entry DOI: 10.2210/pdb4nxi/pdb
• Descriptor: Uncharacterized protein, MAGNESIUM ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: thioredoxin, oxidoreductase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 46647.68

Authors

Albesa-Jove, D.,Urresti, S.,Comino, N.,Guerin, M.E. (deposition date: 2013-12-09, release date: 2014-10-22, Last modification date: 2023-11-08)

• Primary citation: Albesa-Jove, D.,Chiarelli, L.R.,Makarov, V.,Pasca, M.R.,Urresti, S.,Mori, G.,Salina, E.,Vocat, A.,Comino, N.,Mohorko, E.,Ryabova, S.,Pfieiffer, B.,Lopes Ribeiro, A.L.,Rodrigo-Unzueta, A.,Tersa, M.,Zanoni, G.,Buroni, S.,Altmann, K.H.,Hartkoorn, R.C.,Glockshuber, R.,Cole, S.T.,Riccardi, G.,Guerin, M.E.; Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis.; Acs Chem.Biol., 9:1567-1575, 2014; PubMed: 24877756; DOI: 10.1021/cb500149m

Experimental method

X-RAY DIFFRACTION (1.698 Å)