4NWE

Lysozyme UNDER 30 BAR PRESSURE OF NITROUS OXIDE

Summary for 4NWE

• Entry DOI: 10.2210/pdb4nwe/pdb
• Related: 4NWH 4NXA 4NXC 4O4T 4O4Z
• Descriptor: Lysozyme C, NITROUS OXIDE, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: alpha and beta proteins lysozyme-like, hydrolase
• Biological source: Gallus gallus (bantam,chickens)
• Cellular location: Secreted: P00698
• Total number of polymer chains: 1
• Total formula weight: 14446.08

Authors

Colloc'h, N.,Prange, T. (deposition date: 2013-12-06, release date: 2014-09-24, Last modification date: 2024-11-06)

Primary citation

Abraini, J.H.,Marassio, G.,David, H.N.,Vallone, B.,Prange, T.,Colloc'h, N.
Crystallographic Studies with Xenon and Nitrous Oxide Provide Evidence for Protein-dependent Processes in the Mechanisms of General Anesthesia
Anesthesiology, 121:1018-1027, 2014

PubMed Abstract: The mechanisms by which general anesthetics, including xenon and nitrous oxide, act are only beginning to be discovered. However, structural approaches revealed weak but specific protein-gas interactions.

PubMed: 25211169
DOI: 10.1097/ALN.0000000000000435

Experimental method

X-RAY DIFFRACTION (1.58 Å)