4NUV

Heterotetramer structure of Region II from Plasmodium vivax Duffy Binding Protein (PvDBP) bound to the ectodomain of the Duffy Antigen Receptor for Chemokines (DARC)

4NUV の概要

• エントリーDOI: 10.2210/pdb4nuv/pdb
• 関連するPDBエントリー: 4NUU
• 分子名称: Duffy receptor, Duffy antigen/chemokine receptor, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: duffy binding like (dbl) domain fold, gpcr, adhesion, invasion, red blood cell binding, chemokine binding, duffy antigen receptor for chemokines, membrane, membrane protein, protein binding, cell invasion
• 由来する生物種: Plasmodium vivax; 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P22290; Early endosome: Q16570
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 82661.50

構造登録者

Tolia, N.H. (登録日: 2013-12-04, 公開日: 2014-02-05, 最終更新日: 2024-03-13)

• 主引用文献: Batchelor, J.D.,Malpede, B.M.,Omattage, N.S.,Dekoster, G.T.,Henzler-Wildman, K.A.,Tolia, N.H.; Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC.; Plos Pathog., 10:e1003869-e1003869, 2014; PubMed: 24415938; DOI: 10.1371/journal.ppat.1003869

実験手法

X-RAY DIFFRACTION (2.6 Å)