4NST
Crystal structure of human Cdk12/Cyclin K in complex with ADP-aluminum fluoride
Summary for 4NST
Entry DOI | 10.2210/pdb4nst/pdb |
Descriptor | Cyclin-dependent kinase 12, Cyclin-K, ADENOSINE-5'-DIPHOSPHATE, ... (7 entities in total) |
Functional Keywords | transcription, rna polymerase ii, phosphorylation, transferase-transcription complex, transferase/transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9NYV4 O75909 |
Total number of polymer chains | 4 |
Total formula weight | 145829.09 |
Authors | Boesken, C.A.,Farnung, L.,Anand, K.,Geyer, M. (deposition date: 2013-11-29, release date: 2014-03-26, Last modification date: 2023-09-20) |
Primary citation | Bosken, C.A.,Farnung, L.,Hintermair, C.,Merzel Schachter, M.,Vogel-Bachmayr, K.,Blazek, D.,Anand, K.,Fisher, R.P.,Eick, D.,Geyer, M. The structure and substrate specificity of human Cdk12/Cyclin K. Nat Commun, 5:3505-3505, 2014 Cited by PubMed: 24662513DOI: 10.1038/ncomms4505 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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