4NQ6
Bacillus cereus Zn-dependent metallo-beta-lactamase at pH 7 complexed with compound L-CS319
Summary for 4NQ6
Entry DOI | 10.2210/pdb4nq6/pdb |
Related | 4NQ4 4NQ5 4NQ6 4NQ7 |
Descriptor | Beta-lactamase 2, ZINC ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | lactamase, metallo-beta-lactamase superfamily, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bacillus cereus |
Cellular location | Periplasm : P04190 |
Total number of polymer chains | 1 |
Total formula weight | 24830.18 |
Authors | Gonzalez, J.M.,Gonzalez, M.M.,Vila, A.J. (deposition date: 2013-11-23, release date: 2014-11-26, Last modification date: 2024-02-28) |
Primary citation | Hinchliffe, P.,Gonzalez, M.M.,Mojica, M.F.,Gonzalez, J.M.,Castillo, V.,Saiz, C.,Kosmopoulou, M.,Tooke, C.L.,Llarrull, L.I.,Mahler, G.,Bonomo, R.A.,Vila, A.J.,Spencer, J. Cross-class metallo-beta-lactamase inhibition by bisthiazolidines reveals multiple binding modes. Proc. Natl. Acad. Sci. U.S.A., 113:E3745-E3754, 2016 Cited by PubMed: 27303030DOI: 10.1073/pnas.1601368113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report