4NME

Crystal structure of proline utilization A (PutA) from Geobacter sulfurreducens PCA inactivated by N-propargylglycine

4NME の概要

• エントリーDOI: 10.2210/pdb4nme/pdb
• 関連するPDBエントリー: 4NM9 4NMA 4NMB 4NMC 4NMD 4NMF
• 分子名称: Proline dehydrogenase and Delta-1-pyrroline-5-carboxylate dehydrogenase, N-propargylglycine-modified flavin adenine dinucleotide, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: flavoenzyme, rossmann fold, aldehyde dehydrogenase, flavin adenine dinucleotide, nicotinamide adenine dinucleotide, proline catabolism, substrate channeling, bifunctional enzyme, mechanism-based inactivation, oxidoreductase
• 由来する生物種: Geobacter sulfurreducens
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 227439.76

構造登録者

Singh, H.,Tanner, J.J. (登録日: 2013-11-14, 公開日: 2014-02-19, 最終更新日: 2023-09-20)

• 主引用文献: Singh, H.,Arentson, B.W.,Becker, D.F.,Tanner, J.J.; Structures of the PutA peripheral membrane flavoenzyme reveal a dynamic substrate-channeling tunnel and the quinone-binding site.; Proc.Natl.Acad.Sci.USA, 111:3389-3394, 2014; PubMed: 24550478; DOI: 10.1073/pnas.1321621111

実験手法

X-RAY DIFFRACTION (2.088 Å)