4NIP
GVIGIAQ segment 147-153 from Human Superoxide Dismutase
Summary for 4NIP
| Entry DOI | 10.2210/pdb4nip/pdb |
| Related | 1NIN 1NIO |
| Descriptor | GVTGIAQ segment from Superoxide dismutase [Cu-Zn] (2 entities in total) |
| Functional Keywords | steric zipper, cross-beta spine, amyloid fiber, protein fibril |
| Biological source | Homo Sapiens (human) |
| Cellular location | Cytoplasm : P00441 |
| Total number of polymer chains | 1 |
| Total formula weight | 656.77 |
| Authors | Sievers, S.A.,Sawaya, M.R.,Eisenberg, D.,Ivanova, M.I. (deposition date: 2013-11-06, release date: 2013-12-04, Last modification date: 2024-02-28) |
| Primary citation | Ivanova, M.I.,Sievers, S.A.,Guenther, E.L.,Johnson, L.M.,Winkler, D.D.,Galaleldeen, A.,Sawaya, M.R.,Hart, P.J.,Eisenberg, D.S. Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS. Proc.Natl.Acad.Sci.USA, 111:197-201, 2014 Cited by PubMed: 24344300DOI: 10.1073/pnas.1320786110 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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