4NHY
Crystal structure of human OGFOD1, 2-oxoglutarate and iron-dependent oxygenase domain containing 1, in complex with pyridine-2,4-dicarboxylic acid (2,4-PDCA)
Summary for 4NHY
Entry DOI | 10.2210/pdb4nhy/pdb |
Related | 4NHL 4NHM 4NHN 4NHX |
Descriptor | 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, MANGANESE (II) ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | jelly-roll fold, translation, ribosome, double-stranded beta helix, oxygen sensing, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 263162.18 |
Authors | Horita, S.,McDonough, M.A.,Schofield, C.J. (deposition date: 2013-11-05, release date: 2014-11-19, Last modification date: 2023-09-20) |
Primary citation | Horita, S.,Scotti, J.S.,Thinnes, C.,Mottaghi-Taromsari, Y.S.,Thalhammer, A.,Ge, W.,Aik, W.,Loenarz, C.,Schofield, C.J.,McDonough, M.A. Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases. Structure, 23:639-652, 2015 Cited by PubMed: 25728928DOI: 10.1016/j.str.2015.01.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.603 Å) |
Structure validation
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