4NHM
Crystal structure of Tpa1p from Saccharomyces cerevisiae, termination and polyadenylation protein 1, in complex with N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9)
4NHM の概要
エントリーDOI | 10.2210/pdb4nhm/pdb |
関連するPDBエントリー | 4NHK 4NHL 4NHX 4NHY |
分子名称 | PKHD-type hydroxylase TPA1, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE, MANGANESE (II) ION, ... (5 entities in total) |
機能のキーワード | 2-oxoglutarate oxygenase, oxygen sensing, protein synthesis regulation, double-stranded beta helix, jellyroll fold, prolyl hydroxylase, translation, ribosome, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
由来する生物種 | Saccharomyces cerevisiae (Baker's yeast) |
細胞内の位置 | Nucleus : P40032 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 75014.31 |
構造登録者 | |
主引用文献 | Horita, S.,Scotti, J.S.,Thinnes, C.,Mottaghi-Taromsari, Y.S.,Thalhammer, A.,Ge, W.,Aik, W.,Loenarz, C.,Schofield, C.J.,McDonough, M.A. Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases. Structure, 23:639-652, 2015 Cited by PubMed: 25728928DOI: 10.1016/j.str.2015.01.014 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.9 Å) |
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