4NHG

Crystal Structure of 2G12 IgG Dimer

Summary for 4NHG

• Entry DOI: 10.2210/pdb4nhg/pdb
• Descriptor: 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein (3 entities in total)
• Functional Keywords: ig fold, antibody, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 18
• Total formula weight: 437315.78

Authors

Wu, Y.,West Jr., A.P.,Kim, H.J.,Thornton, M.E.,Ward, A.B.,Bjorkman, P.J. (deposition date: 2013-11-05, release date: 2014-02-26, Last modification date: 2019-07-17)

• Primary citation: Wu, Y.,West, A.P.,Kim, H.J.,Thornton, M.E.,Ward, A.B.,Bjorkman, P.J.; Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.; Cell Rep, 5:1443-1455, 2013; PubMed: 24316082; DOI: 10.1016/j.celrep.2013.11.015

Experimental method

X-RAY DIFFRACTION (8.001 Å)