4NE2

Pantothenamide-bound Pantothenate Kinase from Klebsiella pneumoniae

Summary for 4NE2

• Entry DOI: 10.2210/pdb4ne2/pdb
• Related: 4NB4
• Descriptor: Pantothenate kinase, ADENOSINE-5'-DIPHOSPHATE, (R)-N-(3-((2-(benzo[d][1,3]dioxol-5-yl)ethyl)amino)-3-oxopropyl)-2,4-dihydroxy-3,3-dimethylbutanamide, ... (5 entities in total)
• Functional Keywords: protein-substrate complex, transferase
• Biological source: Klebsiella pneumoniae
• Cellular location: Cytoplasm (By similarity): B5XYG3
• Total number of polymer chains: 2
• Total formula weight: 78557.40

Authors

Hughes, S.J.,Antoshchenko, T.,Kim, K.P.,Smil, D.,Park, H.W. (deposition date: 2013-10-28, release date: 2014-02-26, Last modification date: 2023-09-20)

• Primary citation: Hughes, S.J.,Antoshchenko, T.,Kim, K.P.,Smil, D.,Park, H.W.; Structural characterization of a new N-substituted pantothenamide bound to pantothenate kinases from Klebsiella pneumoniae and Staphylococcus aureus.; Proteins, 82:1542-1548, 2014; PubMed: 24470271; DOI: 10.1002/prot.24524

Experimental method

X-RAY DIFFRACTION (1.9 Å)