4NCY

In situ trypsin crystallized on a MiTeGen micromesh with imidazole ligand

Summary for 4NCY

Entry DOI	10.2210/pdb4ncy/pdb
Descriptor	Cationic trypsin, CALCIUM ION, BENZAMIDINE, ... (7 entities in total)
Functional Keywords	imidazole, hydrolase
Biological source	Bos taurus (bovine)
Cellular location	Secreted, extracellular space: P00760
Total number of polymer chains	1
Total formula weight	24406.32
Authors	Yin, X.,Scalia, A.,Leroy, L.,Cuttitta, C.M.,Polizzo, G.M.,Ericson, D.L.,Roessler, C.G.,Campos, O.,Agarwal, R.,Allaire, M.,Orville, A.M.,Jackimowicz, R.,Ma, M.Y.,Sweet, R.M.,Soares, A.S. (deposition date: 2013-10-25, release date: 2014-04-09, Last modification date: 2023-09-20)
Primary citation	Yin, X.,Scalia, A.,Leroy, L.,Cuttitta, C.M.,Polizzo, G.M.,Ericson, D.L.,Roessler, C.G.,Campos, O.,Ma, M.Y.,Agarwal, R.,Jackimowicz, R.,Allaire, M.,Orville, A.M.,Sweet, R.M.,Soares, A.S. Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes. Acta Crystallogr.,Sect.D, 70:1177-1189, 2014 Cited by PubMed: 24816088 DOI: 10.1107/S1399004713034603 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.42 Å)

Structure validation