4NCK

Crystal Structure of Pyrococcus furiosis Rad50 R797G mutation

Summary for 4NCK

Related4NCH 4NCI 4NCJ
DescriptorDNA double-strand break repair Rad50 ATPase, SULFATE ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsadenosine triphosphatase, dna repair, dna binding protein, fungal protein
Biological sourcePyrococcus furiosus
Total number of polymer chains2
Total molecular weight77172.77
Authors
Classen, S.,Williams, G.J.,Arvai, A.S.,Williams, R.S. (deposition date: 2013-10-24, release date: 2014-03-05, Last modification date: 2017-08-02)
Primary citation
Deshpande, R.A.,Williams, G.J.,Limbo, O.,Williams, R.S.,Kuhnlein, J.,Lee, J.H.,Classen, S.,Guenther, G.,Russell, P.,Tainer, J.A.,Paull, T.T.
ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
Embo J., 33:482-500, 2014
PubMed: 24493214 (PDB entries with the same primary citation)
DOI: 10.1002/embj.201386100
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.99 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23321.3%1.3%12.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution