4NCC

Neutralizing antibody to murine norovirus

Summary for 4NCC

• Entry DOI: 10.2210/pdb4ncc/pdb
• Descriptor: Fab fragment light, Fab fragment heavy (3 entities in total)
• Functional Keywords: immunoglobin, antibody, murine norovirus, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 4
• Total formula weight: 93685.15

Authors

Smith, T.,Li, M. (deposition date: 2013-10-24, release date: 2014-02-19, Last modification date: 2014-04-09)

• Primary citation: Kolawole, A.O.,Li, M.,Xia, C.,Fischer, A.E.,Giacobbi, N.S.,Rippinger, C.M.,Proescher, J.B.,Wu, S.K.,Bessling, S.L.,Gamez, M.,Yu, C.,Zhang, R.,Mehoke, T.S.,Pipas, J.M.,Wolfe, J.T.,Lin, J.S.,Feldman, A.B.,Smith, T.J.,Wobus, C.E.; Flexibility in surface-exposed loops in a virus capsid mediates escape from antibody neutralization.; J.Virol., 88:4543-4557, 2014; PubMed: 24501415; DOI: 10.1128/JVI.03685-13

Experimental method

X-RAY DIFFRACTION (2.49 Å)