4N9W

Crystal structure of phosphatidyl mannosyltransferase PimA

Summary for 4N9W

• Entry DOI: 10.2210/pdb4n9w/pdb
• Related: 4NC9
• Descriptor: GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase, GUANOSINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: gt-b, transferase
• Biological source: Mycobacterium smegmatis
• Cellular location: Cell membrane ; Single-pass membrane protein : A0QWG6
• Total number of polymer chains: 1
• Total formula weight: 42046.46

Authors

Giganti, D.,Albesa-Jove, D.,Bellinzoni, M.,Guerin, M.E.,Alzari, P.M. (deposition date: 2013-10-21, release date: 2014-11-12, Last modification date: 2024-02-28)

• Primary citation: Giganti, D.,Albesa-Jove, D.,Urresti, S.,Rodrigo-Unzueta, A.,Martinez, M.A.,Comino, N.,Barilone, N.,Bellinzoni, M.,Chenal, A.,Guerin, M.E.,Alzari, P.M.; Secondary structure reshuffling modulates glycosyltransferase function at the membrane.; Nat.Chem.Biol., 11:16-18, 2015; PubMed: 25402770; DOI: 10.1038/nchembio.1694

Experimental method

X-RAY DIFFRACTION (1.94 Å)