4N9G
Crystal Structure of a Computationally Designed RSV-Presenting Epitope Scaffold And Its Elicited Antibody 17HD9
Summary for 4N9G
Entry DOI | 10.2210/pdb4n9g/pdb |
Descriptor | Antibody 17HD9, Heavy Chain, Antibody 17HD9, Light Chain, Epitope Scaffold rsv_1isea_FFL_001_C, ... (4 entities in total) |
Functional Keywords | antibody, hairpin, epitope scaffold, immune system |
Biological source | Macaca mulatta More |
Total number of polymer chains | 12 |
Total formula weight | 249699.92 |
Authors | Carrico, C.T.D.,Strong, R.K. (deposition date: 2013-10-21, release date: 2014-02-12, Last modification date: 2023-09-20) |
Primary citation | Correia, B.E.,Bates, J.T.,Loomis, R.J.,Baneyx, G.,Carrico, C.,Jardine, J.G.,Rupert, P.,Correnti, C.,Kalyuzhniy, O.,Vittal, V.,Connell, M.J.,Stevens, E.,Schroeter, A.,Chen, M.,Macpherson, S.,Serra, A.M.,Adachi, Y.,Holmes, M.A.,Li, Y.,Klevit, R.E.,Graham, B.S.,Wyatt, R.T.,Baker, D.,Strong, R.K.,Crowe, J.E.,Johnson, P.R.,Schief, W.R. Proof of principle for epitope-focused vaccine design. Nature, 507:201-206, 2014 Cited by PubMed: 24499818DOI: 10.1038/nature12966 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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