4N6O

Crystal structure of reduced legumain in complex with cystatin E/M

4N6O の概要

• エントリーDOI: 10.2210/pdb4n6o/pdb
• 関連するPDBエントリー: 4N6L 4N6M 4N6N
• 分子名称: legumain, cystatin-M, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: complex, cysteine protease, inhibitor, legumain, asparaginyl endopeptidase, reactive center loop, papain, cathepsin, cancer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 48213.94

構造登録者

Dall, E.,Brandstetter, H. (登録日: 2013-10-14, 公開日: 2015-02-11, 最終更新日: 2023-11-15)

• 主引用文献: Dall, E.,Fegg, J.C.,Briza, P.,Brandstetter, H.; Structure and mechanism of an aspartimide-dependent Peptide ligase in human legumain.; Angew.Chem.Int.Ed.Engl., 54:2917-2921, 2015; PubMed: 25630877; DOI: 10.1002/anie.201409135

実験手法

X-RAY DIFFRACTION (1.8 Å)