4MZL

Crystal Structure of MTIP from Plasmodium falciparum in complex with HBS myoA, a hydrogen bond surrogate myoA helix mimetic

4MZL の概要

• エントリーDOI: 10.2210/pdb4mzl/pdb
• 関連するPDBエントリー: 4AOM 4MZJ 4MZK
• 関連するBIRD辞書のPRD_ID: PRD_001188
• 分子名称: Myosin A tail domain interacting protein, hydrogen bond surrogate (HBS) myoA helix mimetic (3 entities in total)
• 機能のキーワード: actomyosin motor, stapled peptides, protein binding-inhibitor complex, alpha-helix mimetic, protein binding/inhibitor
• 由来する生物種: Plasmodium falciparum 3D7; 詳細
• 細胞内の位置: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : 4MZL
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 37157.59

構造登録者

Douse, C.H.,Garnett, J.A.,Maas, S.J.,Cota, E.,Tate, E.W. (登録日: 2013-09-30, 公開日: 2013-11-06, 最終更新日: 2023-06-07)

• 主引用文献: Douse, C.H.,Maas, S.J.,Thomas, J.C.,Garnett, J.A.,Sun, Y.,Cota, E.,Tate, E.W.; Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein-Helix Interaction.; Acs Chem.Biol., 8:506-512, 2014; PubMed: 25084543; DOI: 10.1021/cb500271c

実験手法

X-RAY DIFFRACTION (2.01 Å)