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4MZ7

Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase

Summary for 4MZ7
Entry DOI10.2210/pdb4mz7/pdb
DescriptorDeoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywordshd-domain, hydrolase, dntp binding, phosphorylation
Biological sourceHomo sapiens (human)
Cellular locationNucleus : Q9Y3Z3
Total number of polymer chains2
Total formula weight128178.88
Authors
Zhu, C.,Gao, W.,Zhao, K.,Qin, X.,Zhang, Y.,Peng, X.,Zhang, L.,Dong, Y.,Zhang, W.,Li, P.,Wei, W.,Gong, Y.,Yu, X.F. (deposition date: 2013-09-29, release date: 2013-11-20, Last modification date: 2023-11-08)
Primary citationZhu, C.,Gao, W.,Zhao, K.,Qin, X.,Zhang, Y.,Peng, X.,Zhang, L.,Dong, Y.,Zhang, W.,Li, P.,Wei, W.,Gong, Y.,Yu, X.F.
Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase
Nat Commun, 4:2722-2722, 2013
Cited by
PubMed: 24217394
DOI: 10.1038/ncomms3722
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

건을2024-03-27부터공개중

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