4MZ7
Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase
Summary for 4MZ7
Entry DOI | 10.2210/pdb4mz7/pdb |
Descriptor | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | hd-domain, hydrolase, dntp binding, phosphorylation |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q9Y3Z3 |
Total number of polymer chains | 2 |
Total formula weight | 128178.88 |
Authors | |
Primary citation | Zhu, C.,Gao, W.,Zhao, K.,Qin, X.,Zhang, Y.,Peng, X.,Zhang, L.,Dong, Y.,Zhang, W.,Li, P.,Wei, W.,Gong, Y.,Yu, X.F. Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase Nat Commun, 4:2722-2722, 2013 Cited by PubMed: 24217394DOI: 10.1038/ncomms3722 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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