4MXF

X-ray structure of the adduct between bovine pancreatic ribonuclease and Auoxo6, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers

4MXF の概要

• エントリーDOI: 10.2210/pdb4mxf/pdb
• 関連するPDBエントリー: 1JVT 1JVU 1JVV 4L55 4LFX
• 分子名称: Ribonuclease pancreatic, GOLD ION (3 entities in total)
• 機能のキーワード: ribonuclease fold, hydrolase, rna
• 由来する生物種: Bos taurus (bovine,cow,domestic cattle,domestic cow)
• 細胞内の位置: Secreted: P61823
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 27613.62

構造登録者

Russo Krauss, I.,Vergara, A.,Merlino, A. (登録日: 2013-09-26, 公開日: 2013-12-25, 最終更新日: 2023-09-20)

• 主引用文献: Messori, L.,Scaletti, F.,Massai, L.,Cinellu, M.A.,Russo Krauss, I.,di Martino, G.,Vergara, A.,Paduano, L.,Merlino, A.; Interactions of gold-based drugs with proteins: crystal structure of the adduct formed between ribonuclease A and a cytotoxic gold(iii) compound.; Metallomics, 6:233-236, 2014; PubMed: 24287583; DOI: 10.1039/c3mt00265a

実験手法

X-RAY DIFFRACTION (2.25 Å)