4MX6

Crystal structure of a trap periplasmic solute binding protein from shewanella oneidensis (SO_3134), target EFI-510275, with bound succinate

Summary for 4MX6

• Entry DOI: 10.2210/pdb4mx6/pdb
• Descriptor: TRAP-type C4-dicarboxylate:H+ symport system substrate-binding component DctP, SUCCINIC ACID, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: trap periplasmic solute binding family, enzyme function initiative, efi, structural genomics, transport protein
• Biological source: Shewanella oneidensis
• Total number of polymer chains: 1
• Total formula weight: 38857.13

Authors

Vetting, M.W.,Toro, R.,Bhosle, R.,Al Obaidi, N.F.,Morisco, L.L.,Wasserman, S.R.,Sojitra, S.,Zhao, S.,Stead, M.,Attonito, J.D.,Scott Glenn, A.,Chowdhury, S.,Evans, B.,Hillerich, B.,Love, J.,Seidel, R.D.,Imker, H.J.,Jacobson, M.P.,Gerlt, J.A.,Almo, S.C.,Enzyme Function Initiative (EFI) (deposition date: 2013-09-25, release date: 2013-10-16, Last modification date: 2024-02-28)

• Primary citation: Vetting, M.W.,Al-Obaidi, N.,Zhao, S.,San Francisco, B.,Kim, J.,Wichelecki, D.J.,Bouvier, J.T.,Solbiati, J.O.,Vu, H.,Zhang, X.,Rodionov, D.A.,Love, J.D.,Hillerich, B.S.,Seidel, R.D.,Quinn, R.J.,Osterman, A.L.,Cronan, J.E.,Jacobson, M.P.,Gerlt, J.A.,Almo, S.C.; Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.; Biochemistry, 54:909-931, 2015; PubMed: 25540822; DOI: 10.1021/bi501388y

Experimental method

X-RAY DIFFRACTION (1.1 Å)