4MWZ

Crystal structure of N-methyl transferase from Plasmodium vivax complexed with S-adenosyl methionine, phosphate and amodiaquine

Summary for 4MWZ

• Entry DOI: 10.2210/pdb4mwz/pdb
• Related: 4IV0
• Descriptor: Phosphoethanolamine N-methyltransferase, putative, S-ADENOSYLMETHIONINE, PHOSPHATE ION, ... (6 entities in total)
• Functional Keywords: rossmann fold, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Plasmodium vivax
• Total number of polymer chains: 2
• Total formula weight: 63912.78

Authors

Lukk, T.,Nair, S.K. (deposition date: 2013-09-25, release date: 2014-10-01, Last modification date: 2023-09-20)

• Primary citation: Lukk, T.,Nair, S.K.,Mamoun, C.B.; Phosphoethanolamine N-methyl transferase is a Malarial drug target; to be published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)