4MUC
The 4th and 5th C-terminal domains of Factor H related protein 1
Summary for 4MUC
Entry DOI | 10.2210/pdb4muc/pdb |
Descriptor | Complement factor H-related protein 1, SULFATE ION (2 entities in total) |
Functional Keywords | sushi domains, complement alternative pathway, factor h related proteins, immune system |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: Q03591 |
Total number of polymer chains | 2 |
Total formula weight | 29150.94 |
Authors | Bhattacharjee, A.,Goldman, A.,Kolodziejczyk, R.,Jokiranta, T.S. (deposition date: 2013-09-21, release date: 2015-02-18, Last modification date: 2015-05-06) |
Primary citation | Bhattacharjee, A.,Reuter, S.,Trojnar, E.,Kolodziejczyk, R.,Seeberger, H.,Hyvarinen, S.,Uzonyi, B.,Szilagyi, A.,Prohaszka, Z.,Goldman, A.,Jozsi, M.,Jokiranta, T.S. The Major Autoantibody Epitope on Factor H in Atypical Hemolytic Uremic Syndrome Is Structurally Different from Its Homologous Site in Factor H-related Protein 1, Supporting a Novel Model for Induction of Autoimmunity in This Disease. J.Biol.Chem., 290:9500-9510, 2015 Cited by PubMed: 25659429DOI: 10.1074/jbc.M114.630871 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.897 Å) |
Structure validation
Download full validation report