4MUC

The 4th and 5th C-terminal domains of Factor H related protein 1

4MUC の概要

• エントリーDOI: 10.2210/pdb4muc/pdb
• 分子名称: Complement factor H-related protein 1, SULFATE ION (2 entities in total)
• 機能のキーワード: sushi domains, complement alternative pathway, factor h related proteins, immune system
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted: Q03591
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29150.94

構造登録者

Bhattacharjee, A.,Goldman, A.,Kolodziejczyk, R.,Jokiranta, T.S. (登録日: 2013-09-21, 公開日: 2015-02-18, 最終更新日: 2015-05-06)

• 主引用文献: Bhattacharjee, A.,Reuter, S.,Trojnar, E.,Kolodziejczyk, R.,Seeberger, H.,Hyvarinen, S.,Uzonyi, B.,Szilagyi, A.,Prohaszka, Z.,Goldman, A.,Jozsi, M.,Jokiranta, T.S.; The Major Autoantibody Epitope on Factor H in Atypical Hemolytic Uremic Syndrome Is Structurally Different from Its Homologous Site in Factor H-related Protein 1, Supporting a Novel Model for Induction of Autoimmunity in This Disease.; J.Biol.Chem., 290:9500-9510, 2015; PubMed: 25659429; DOI: 10.1074/jbc.M114.630871

実験手法

X-RAY DIFFRACTION (2.897 Å)