4MTA
Crystal structure of Pim-1 kinase domain in complex with 2-methyl-5-phenylfuran-3-carboxylic acid
Summary for 4MTA
Entry DOI | 10.2210/pdb4mta/pdb |
Descriptor | Serine/threonine-protein kinase pim-1, 2-methyl-5-phenylfuran-3-carboxylic acid, GLYCEROL, ... (4 entities in total) |
Functional Keywords | serine/threonine-protein kinase, atp-binding, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309 |
Total number of polymer chains | 1 |
Total formula weight | 33140.58 |
Authors | Scheufler, C.,Be, C. (deposition date: 2013-09-19, release date: 2015-01-14, Last modification date: 2023-09-20) |
Primary citation | Kutchukian, P.S.,Wassermann, A.M.,Lindvall, M.K.,Wright, S.K.,Ottl, J.,Jacob, J.,Scheufler, C.,Marzinzik, A.,Brooijmans, N.,Glick, M. Large scale meta-analysis of fragment-based screening campaigns: privileged fragments and complementary technologies. J Biomol Screen, 20:588-596, 2015 Cited by PubMed: 25550355DOI: 10.1177/1087057114565080 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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