4MTA

Crystal structure of Pim-1 kinase domain in complex with 2-methyl-5-phenylfuran-3-carboxylic acid

4MTA の概要

• エントリーDOI: 10.2210/pdb4mta/pdb
• 分子名称: Serine/threonine-protein kinase pim-1, 2-methyl-5-phenylfuran-3-carboxylic acid, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: serine/threonine-protein kinase, atp-binding, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33140.58

構造登録者

Scheufler, C.,Be, C. (登録日: 2013-09-19, 公開日: 2015-01-14, 最終更新日: 2023-09-20)

• 主引用文献: Kutchukian, P.S.,Wassermann, A.M.,Lindvall, M.K.,Wright, S.K.,Ottl, J.,Jacob, J.,Scheufler, C.,Marzinzik, A.,Brooijmans, N.,Glick, M.; Large scale meta-analysis of fragment-based screening campaigns: privileged fragments and complementary technologies.; J Biomol Screen, 20:588-596, 2015; PubMed: 25550355; DOI: 10.1177/1087057114565080

実験手法

X-RAY DIFFRACTION (2.2 Å)