4MQL

Crystal structure of Antigen 85C-C209S mutant

Summary for 4MQL

• Entry DOI: 10.2210/pdb4mql/pdb
• Related: 4MQM
• Descriptor: Diacylglycerol acyltransferase/mycolyltransferase Ag85C, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
• Functional Keywords: acyltransferase, transferase
• Biological source: Mycobacterium tuberculosis
• Cellular location: Secreted (By similarity): P0A4V4
• Total number of polymer chains: 1
• Total formula weight: 33716.28

Authors

Favrot, L.,Grzegorzewicz, A.E.,Lajiness, D.H.,Marvin, R.K.,Boucau, J.,Isailovic, D.,Jackson, M.,Ronning, D.R. (deposition date: 2013-09-16, release date: 2013-11-13, Last modification date: 2024-02-28)

• Primary citation: Favrot, L.,Grzegorzewicz, A.E.,Lajiness, D.H.,Marvin, R.K.,Boucau, J.,Isailovic, D.,Jackson, M.,Ronning, D.R.; Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen.; Nat Commun, 4:2748-2748, 2013; PubMed: 24193546; DOI: 10.1038/ncomms3748

Experimental method

X-RAY DIFFRACTION (1.3 Å)