4MK5
6-(3-methoxyphenyl)pyridine-2,3-diol bound to influenza 2009 pH1N1 endonuclease
Summary for 4MK5
Entry DOI | 10.2210/pdb4mk5/pdb |
Related | 4LN7 4M4Q 4M5O 4M5Q 4M5R 4M5V 4MK1 4MK2 |
Descriptor | POLYMERASE PA, MANGANESE (II) ION, SULFATE ION, ... (6 entities in total) |
Functional Keywords | cap-snatching, rna binding protein, rna binding protein-inhibitor complex, rna binding protein/inhibitor |
Biological source | INFLUENZA A VIRUS (A/LIMA/WRAIR1695P/2009(H1N1)) |
Total number of polymer chains | 1 |
Total formula weight | 29045.44 |
Authors | Bauman, J.D.,Patel, D.,Das, K.,Arnold, E. (deposition date: 2013-09-04, release date: 2013-09-25, Last modification date: 2024-02-28) |
Primary citation | Bauman, J.D.,Patel, D.,Baker, S.F.,Vijayan, R.S.,Xiang, A.,Parhi, A.K.,Martinez-Sobrido, L.,Lavoie, E.J.,Das, K.,Arnold, E. Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8:2501-2508, 2013 Cited by PubMed: 23978130DOI: 10.1021/cb400400j PDB entries with the same primary citation |
Experimental method |
Structure validation
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