4MJU
Influenza Neuraminidase in complex with a novel antiviral compound
Summary for 4MJU
Entry DOI | 10.2210/pdb4mju/pdb |
Related | 4MJU |
Descriptor | Neuraminidase, (5R,9R,10S)-10-(acetylamino)-2-amino-4-oxo-9-(pentan-3-yloxy)-1-thia-3-azaspiro[4.5]deca-2,6-diene-7-carboxylic acid, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | sialidase, neuraminidase, viral protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Influenza A virus |
Cellular location | Virion membrane : Q07599 |
Total number of polymer chains | 1 |
Total formula weight | 43474.92 |
Authors | Kerry, P.S. (deposition date: 2013-09-04, release date: 2014-01-15, Last modification date: 2024-10-16) |
Primary citation | Mohan, S.,Kerry, P.S.,Bance, N.,Niikura, M.,Pinto, B.M. Serendipitous discovery of a potent influenza virus a neuraminidase inhibitor. Angew.Chem.Int.Ed.Engl., 53:1076-1080, 2014 Cited by PubMed: 24339250DOI: 10.1002/anie.201308142 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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