4MJ0

BK Polyomavirus VP1 pentamer in complex with GD3 oligosaccharide

Summary for 4MJ0

• Entry DOI: 10.2210/pdb4mj0/pdb
• Related: 3BWQ 3BWR 3NXD 4MJ1
• Descriptor: VP1 capsid protein, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid, ... (7 entities in total)
• Functional Keywords: antiparallel beta sandwich, jelly-roll topology, viral protein, polyomavirus, receptor-switching, glycan receptor, virus major capsid protein, attachment to host-cell surface receptors
• Biological source: BK polyomavirus (BKPyV)
• Total number of polymer chains: 5
• Total formula weight: 155015.64

Authors

Neu, U.,Stroh, L.J.,Stehle, T. (deposition date: 2013-09-03, release date: 2013-11-06, Last modification date: 2024-04-03)

• Primary citation: Neu, U.,Allen, S.A.,Blaum, B.S.,Liu, Y.,Frank, M.,Palma, A.S.,Stroh, L.J.,Feizi, T.,Peters, T.,Atwood, W.J.,Stehle, T.; A Structure-Guided Mutation in the Major Capsid Protein Retargets BK Polyomavirus.; Plos Pathog., 9:e1003688-e1003688, 2013; PubMed: 24130487; DOI: 10.1371/journal.ppat.1003688

Experimental method

X-RAY DIFFRACTION (1.7 Å)