4MHH

Crystal structure of Fab H5M9 in complex with influenza virus hemagglutinin from A/Viet Nam/1203/2004 (H5N1)

4MHH の概要

• エントリーDOI: 10.2210/pdb4mhh/pdb
• 関連するPDBエントリー: 2FK0 3GBM 4MHI 4MHJ
• 分子名称: Hemagglutinin HA1 chain, H5M9 antibody, light chain (kappa), Hemagglutinin HA2 chain, ... (9 entities in total)
• 機能のキーワード: h5n1 influenza virus, broadly neutralizing murine antibody, escape mutant, passive immunotherapy, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Influenza A virus; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 330812.84

構造登録者

Zhu, X.,Wilson, I.A. (登録日: 2013-08-29, 公開日: 2013-10-02, 最終更新日: 2023-09-20)

• 主引用文献: Zhu, X.,Guo, Y.H.,Jiang, T.,Wang, Y.D.,Chan, K.H.,Li, X.F.,Yu, W.,McBride, R.,Paulson, J.C.,Yuen, K.Y.,Qin, C.F.,Che, X.Y.,Wilson, I.A.; A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.; J.Virol., 87:12619-12635, 2013; PubMed: 24049169; DOI: 10.1128/JVI.01577-13

実験手法

X-RAY DIFFRACTION (3.564 Å)