4MG3

Crystal Structural Analysis of 2A Protease from Coxsackievirus A16

Summary for 4MG3

• Entry DOI: 10.2210/pdb4mg3/pdb
• Descriptor: Protease 2A, ZINC ION, PENTAETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: beta barrel, hydrolase
• Biological source: Coxsackievirus A16
• Cellular location: Capsid protein VP0: Virion . Capsid protein VP4: Virion . Capsid protein VP2: Virion . Capsid protein VP3: Virion . Capsid protein VP1: Virion . Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3AB: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Viral protein genome-linked: Virion . Protease 3C: Host cytoplasm . Protein 3CD: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . RNA-directed RNA polymerase: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : Q9QF31
• Total number of polymer chains: 2
• Total formula weight: 32362.93

Authors

Sun, Y.,Wang, X.,Dang, M.,Yuan, S. (deposition date: 2013-08-28, release date: 2014-03-26, Last modification date: 2017-11-15)

• Primary citation: Sun, Y.,Wang, X.,Yuan, S.,Dang, M.,Li, X.,Zhang, X.C.,Rao, Z.; An open conformation determined by a structural switch for 2A protease from coxsackievirus A16.; Protein Cell, 4:782-792, 2013; PubMed: 24026848; DOI: 10.1007/s13238-013-3914-z

Experimental method

X-RAY DIFFRACTION (1.798 Å)