4MG3
Crystal Structural Analysis of 2A Protease from Coxsackievirus A16
Summary for 4MG3
Entry DOI | 10.2210/pdb4mg3/pdb |
Descriptor | Protease 2A, ZINC ION, PENTAETHYLENE GLYCOL, ... (5 entities in total) |
Functional Keywords | beta barrel, hydrolase |
Biological source | Coxsackievirus A16 |
Cellular location | Capsid protein VP0: Virion . Capsid protein VP4: Virion . Capsid protein VP2: Virion . Capsid protein VP3: Virion . Capsid protein VP1: Virion . Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3AB: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Viral protein genome-linked: Virion . Protease 3C: Host cytoplasm . Protein 3CD: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . RNA-directed RNA polymerase: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : Q9QF31 |
Total number of polymer chains | 2 |
Total formula weight | 32362.93 |
Authors | |
Primary citation | Sun, Y.,Wang, X.,Yuan, S.,Dang, M.,Li, X.,Zhang, X.C.,Rao, Z. An open conformation determined by a structural switch for 2A protease from coxsackievirus A16. Protein Cell, 4:782-792, 2013 Cited by PubMed: 24026848DOI: 10.1007/s13238-013-3914-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.798 Å) |
Structure validation
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