4MFL

The crystal structure of acyltransferase in complex with decanoyl-CoA and Tei pseudoaglycone

Summary for 4MFL

Entry DOI	10.2210/pdb4mfl/pdb
Related	4MFJ 4MFK 4MFP 4MFQ 4MFS 4MFT 4MFW 4MFX 4MFY 4MG0 4MG1
Related PRD ID	PRD_001158
Descriptor	Putative uncharacterized protein tcp24, Teicoplanin pseudoaglycone, SULFATE ION, ... (8 entities in total)
Functional Keywords	gnat, acyltransferase, acyl-coa, transferase-antibiotic complex, transferase/antibiotic
Biological source	Actinoplanes teichomyceticus More
Total number of polymer chains	2
Total formula weight	42201.83
Authors	Lyu, S.Y.,Liu, Y.C.,Chang, C.Y.,Huang, C.J.,Li, T.L. (deposition date: 2013-08-28, release date: 2014-09-03, Last modification date: 2023-12-06)
Primary citation	Lyu, S.Y.,Liu, Y.C.,Chang, C.Y.,Huang, C.J.,Chiu, Y.H.,Huang, C.M.,Hsu, N.S.,Lin, K.H.,Wu, C.J.,Tsai, M.D.,Li, T.L. Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136:10989-10995, 2014 Cited by PubMed: 25095906 DOI: 10.1021/ja504125v PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation