4M7M

Crystal structure of the R111K:R132Q:Y134F:T54V:R59W:A32W mutant of the Cellular Retinoic Acid Binding Protein Type II in complex with All-Trans Retinal at 2.57 Angstrom Resolution

Summary for 4M7M

Related2G7B 2G78 2FR3 3F8A 4EXZ 4EEJ 4EFG 3FEP 4I9R 4I9S 4M6S
DescriptorCellular retinoic acid-binding protein 2, RETINAL (3 entities in total)
Functional Keywordsprotein engineering, wavelength regulation, ph-sensing, retinylidene psb, iminium, transport protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P29373
Total number of polymer chains1
Total molecular weight15935.34
Authors
Nosrati, M.,Geiger, J.H. (deposition date: 2013-08-12, release date: 2013-10-09, Last modification date: 2014-02-19)
Primary citation
Berbasova, T.,Nosrati, M.,Vasileiou, C.,Wang, W.,Lee, K.S.,Yapici, I.,Geiger, J.H.,Borhan, B.
Rational Design of a Colorimetric pH Sensor from a Soluble Retinoic Acid Chaperone.
J.Am.Chem.Soc., 135:16111-16119, 2013
PubMed: 24059243 (PDB entries with the same primary citation)
DOI: 10.1021/ja404900k
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.571 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.236906.1%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report